1. Place the reference slide and the donor block on the microscope stage, and mark the position with an oil pen, where you intend to extract the sample tissue . 2. Extract the marked tissue from the donor block by using Quick-RayTM needle 3. Deliver the extracted tissue into the corresponding holes of the recipient block pre-made by Unitma, with Quick-RayTM needle 4. Put the completed recipient block into the base mold with the face to be sectioned down and place them in an oven at 70กษ for about 45 minutes or until the block is completely transparent, then take them out from the oven. 5. Place an embedding cassette on the top of transparent block and dispense liquid paraffin into the base mold adequately covering the cassette. 6. Solidify the block in cold plate 7. Sectioning by a mircotome    8. Proceed the next steps