Diabetes is a disorder that affects the body's ability to make or use insulin. Insulin is a hormone produced in the pancreas that allows the body¡¯s cells to process glucose (blood sugar) for energy. After a meal, sugars(mainly glucose) are absorbed into the bloodstream and Insulin is secreted by the pancreas. Most cells of the body have insulin receptors for cells to absorb sugar from the blood. When insulin is not secreted efficiently or the body cannot appropriately use insulin, cells of the body cannot access the energy contained in the glucose, and the levels of glucose in blood becomes higher than in normal individuals causing the onset of Diabetes. According to many health reports, as many as 20% or more of the total world population has some degree of high level of sugar in their blood. In Type 1 diabetes, the body no longer produces insulin and in Type 2 diabetes, the body cannot use insulin properly. The causes of diabetes are complex and only partly understood. Risk factors include genetics, family history, excess weight, physical inactivity, age, race and environment. Signs and symptoms vary and are not always present Possible indicators of diabetes may include unexplained weight loss, frequent infections, slow healing of wounds, vision problems and excessive thirst, urination and hunger. Physicians rely on glucose tests for diagnosis. Treatment includes diet, exercise and often medications like insulin therapy, antidiabetic agents, cholesterol drugs and blood pressure drugs, etc. All people with type 1 diabetes and Wolfram syndrome and eventually all people with latent autoimmune diabetes of adulthood require regular insulin therapy to live. Some people with other forms of diabetes, including gestational diabetes, type 2 diabetes, secondary diabetes and maturity-onset diabetes of the young, also are prescribed insulin. Forms of insulin administration include syringe injections, insulin pumps, insulin pens, jet injectors and inhaled insulin. Patients require regular medical care and must perform self care including glucose monitoring, ketone tests and foot care. By controlling glucose and following other aspects of their treatment plan, patients can avoid complications such as chronic kidney failure sometimes leading to dialysis, blindness, amputation and diabetic coma.